The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
Jan. 26, 2017
Applicant:
Svenska Vaccinfabriken Produktion Ab, Stockholm, SE;
Inventors:
Matti Sällberg, Stockholm, SE;
Lars Frelin, Älvsjö, SE;
Assignee:
Svenska Vaccinfabriken Produktion AB, Stockholm, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/02 (2006.01); C07K 14/005 (2006.01); A61K 39/29 (2006.01); A61K 39/39 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/29 (2013.01); A61K 39/12 (2013.01); A61K 39/39 (2013.01); C07K 14/005 (2013.01); C07K 14/02 (2013.01); A61K 2039/55538 (2013.01); A61K 2039/70 (2013.01); C07K 2319/00 (2013.01); C12N 2730/10122 (2013.01); C12N 2730/10134 (2013.01); C12N 2760/10122 (2013.01); C12N 2760/10134 (2013.01);
Abstract
Disclosed herein are chimeric genes, compositions of chimeric genes, and compositions of polypeptides that are useful for the generation, enhancement, or improvement of an immune response to a target antigen. Some embodiments of the compositions include chimeric genes encoding hepatitis D antigen (HDAg) protein in combination with one or more self-cleavage 2A polypeptides and a preS 1 polypeptide. In certain embodiments the self-cleavage polypeptide is P2A.