The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
Sep. 24, 2015
Applicant:
Aileron Therapeutics, Inc., Cambridge, MA (US);
Inventors:
David Allen Annis, Cambridge, MA (US);
Krzysztof Darlak, Newton, MA (US);
Chris Rhodes, San Diego, CA (US);
Sonoko Kanai, Basel, CH;
Joerg Hoernschemeyer, Loerrach, DE;
Michaela Grass, Rheinfelden, DE;
Assignee:
Aileron Therapeutics, Inc., Watertown, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); A61K 9/00 (2006.01); A61K 38/10 (2006.01); A61K 47/26 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/12 (2013.01); A61K 9/0019 (2013.01); A61K 38/10 (2013.01); A61K 47/26 (2013.01); A61P 35/00 (2018.01);
Abstract
Aqueous pharmaceutical formulations, for parenteral administration, comprising peptidomimetic macrocycle or a pharmaceutically acceptable salt thereof wherein the peptidomimetic macrocycle binds to MDM2 and/or MDMX proteins are disclosed. Also disclosed are methods of treating diseases and disorders using the aqueous pharmaceutical formulations disclosed herein.