The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
Apr. 27, 2017
Zhongcheng Investment Management (Shanghai) Co., Ltd, Shanghai, CN;
Ningsheng Shao, Beijing, CN;
Guang Yang, Beijing, CN;
Liangyou Wang, Suzhou, CN;
Hongmei Ding, Beijing, CN;
Yaping Gao, Beijing, CN;
Shaohua Li, Beijing, CN;
Hui Li, Beijing, CN;
Jie Li, Beijing, CN;
Jie Dong, Beijing, CN;
Wenhui Xia, Haikou, CN;
Xiaoping Liang, Haikou, CN;
ZHONGCHENG INVESTMENT MANAGEMENT (SHANGHAI) CO., LTD, Shanghai, CN;
Abstract
The invention relates to a chemosynthetic cyclo-hepta modified peptide capable of inhibiting toxins ofand a use thereof. The chemosynthetic peptide can specifically inhibit production of the toxins ofby means of the binding of the RNAIII activator protein by aautocrine. The invention also relates to the use of the chemosynthetic peptide in the pharmaceutical field. The sequence general formula of the chemosynthetic cyclo-hepta modified peptide is CH—(CH)m-X-G-(CQHWWHWYC)—(R)n-Y. The results show that the modified peptide can be dissolved well in water and has good activity against the toxins of