The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2021

Filed:

Nov. 19, 2019
Applicant:

Universite DE Liege, Liege, BE;

Inventors:

Cécile Oury, Liege, BE;

Patrizio Lancellotti, Liege, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/04 (2006.01); A61P 31/04 (2006.01); A61L 2/00 (2006.01); A61L 2/16 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61L 2/0082 (2013.01); A61L 2/16 (2013.01); A61P 31/04 (2018.01); A61L 2202/24 (2013.01);
Abstract

A method for treatment of a bacterial infection in a host mammal in need of such treatment or a method of administering to the host mammal an effective amount of a Triazolo(4,5-d)pyrimidine of formula(I): wherein Ris Calkyl optionally substituted by one or more halogen atoms; Ris a phenyl group, optionally substituted by one or more halogen atoms; Rand Rare both hydroxyl; R is XOH, wherein X is CH, OCHCH, or a bond, and wherein when X is a bond, R is OH; or a pharmaceutical acceptable salt, provided that when X is CHor a bond, Ris not propyl; when X is CHand Ris CHCHCF, butyl or pentyl, the phenyl group at Rmust be substituted by fluorine; when X is OCHCHand Ris propyl, the phenyl group at Rmust be substituted by fluorine.


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