The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2021

Filed:

Jan. 17, 2017
Applicant:

Universidad Miguel Hernandez DE Elche, Alicante, ES;

Inventors:

Antonio Vicente Ferrer Montiel, Alicante, ES;

Asia Fernandez Carvajal, Alicante, ES;

Carlos Belmonte Martinez, Alicante, ES;

Juana Gallar Martinez, Alicante, ES;

Roberto De La Torre, Alicante, ES;

Armando Genazzani, Novara, IT;

Gian Cesare Tron, Novara, IT;

Valentina Mercalli, Novara, IT;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/04 (2006.01); C07D 249/06 (2006.01); C07D 401/04 (2006.01); H02G 3/08 (2006.01); H02G 3/06 (2006.01); A61K 31/4192 (2006.01); A61P 27/04 (2006.01); A61P 15/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4192 (2013.01); A61P 15/02 (2018.01); A61P 27/04 (2018.01); C07D 249/04 (2013.01); C07D 249/06 (2013.01); C07D 401/04 (2013.01); H02G 3/0675 (2013.01); H02G 3/088 (2013.01);
Abstract

The invention relates to compounds having formula (I) wherein A is selected from the group consisting of: a) optionally substituted (C-C) alkyl; b) optionally substituted (C-C) cycloalkyl; c) optionally substituted (C-C) aryl; d) optionally substituted (C-C) heteroaryl; e) C(O)—(C-C) aryl, in which group (C-C) aryl is optionally substituted; f) C(O)—(C-C) heteroaryl, in which group (C-C) heteroaryl is optionally substituted; g) CH(OH)—(C-C) aryl, in which group (C-C) aryl is optionally substituted; and h) CH(OH)—(C-C) heteroaryl, in which group (C-C) heteroaryl is optionally substituted. The invention also relates to methods for the production of said compounds, to pharmaceutical and veterinary compositions comprising said compounds and to the therapeutic uses thereof, such as for the prevention and/or treatment of dry eye syndrome, vaginal dryness and/or burning mouth syndrome.


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