The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2021

Filed:

Oct. 17, 2016
Applicants:

Georgetown University, Washington, DC (US);

University of Rochester, Rochester, NY (US);

Inventors:

Howard J. Federoff, Bethesda, MD (US);

Massimo S. Fiandaca, Millersville, MD (US);

Amrita K. Cheema, Potomac, MD (US);

Mark E. Mapstone, Pittsford, NY (US);

Xiaogang Zhong, College Park, MD (US);

Assignees:

Georgetown University, Washington, DC (US);

University of Rochester, Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12Q 1/68 (2018.01); G01N 33/567 (2006.01); G01N 33/68 (2006.01); G16B 20/00 (2019.01); G16H 50/30 (2018.01); G16H 50/20 (2018.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); G16B 20/00 (2019.02); G16H 50/20 (2018.01); G16H 50/30 (2018.01); G01N 2570/00 (2013.01); G01N 2800/2814 (2013.01); G01N 2800/60 (2013.01);
Abstract

The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing at least one plasma sample from the subject to determine a value of the subject's proteomic profile and comparing the value of the subject's proteomic profile with the value of a normal proteomic profile. A change in the value of the subject's proteomic profile, over normal values is indicative that the subject has an increased risk of suffering from memory impairment compared to a normal individual.


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