The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2021
Filed:
Jul. 26, 2017
Applicant:
Polichem S.a., Luxembourg, LU;
Inventors:
Roberto Burioni, Milan, IT;
Massimo Clementi, Milan, IT;
Assignee:
Polichem S.A., Luxembourg, LU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/08 (2006.01); A61K 31/522 (2006.01); A61K 31/662 (2006.01); A61K 39/42 (2006.01); A61K 45/06 (2006.01); A61P 31/22 (2006.01); A61P 27/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/087 (2013.01); A61K 31/522 (2013.01); A61K 31/662 (2013.01); A61K 39/42 (2013.01); A61K 45/06 (2013.01); A61P 27/00 (2018.01); A61P 31/22 (2018.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C12N 2710/16611 (2013.01);
Abstract
The present invention relates to a combination comprising HSV-1 and HSV-2 binding monoclonal antibodies or fragments thereof and antiviral agents, the pharmaceutical formulations comprising said combination, optionally together with an excipient pharmaceutically acceptable and its use in the prophylaxis and/or treatment of herpes virus infections, including genital herpes, HSV gingivostomatitis and recurrent herpes labialis, herpes simplex encephalitis (HSE), neonatal HSV, HSV disease in the immunocompromised host and HSV keratitis keratoconjunctivitis.