The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2021

Filed:

Sep. 02, 2016
Applicant:

Eloxx Pharmaceuticals Ltd., Rehovot, IL;

Inventors:

Timor Baasov, Haifa, IL;

Shmuel Tuvia, Natania, IL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/23 (2006.01); C07H 15/224 (2006.01);
U.S. Cl.
CPC ...
C07H 15/224 (2013.01); C07H 15/23 (2013.01);
Abstract

Novel aminoglycosides, represented by Formulae Ia and Ib, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic diseases and disorders, such as diseases and disorders associated with stop codon mutations.


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