The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2021

Filed:

Apr. 12, 2016
Applicants:

Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;

Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Wangyang Tu, Shanghai, CN;

Guoji Xu, Shanghai, CN;

Haitang Zhang, Shanghai, CN;

Jiangtao Chi, Shanghai, CN;

Qing Dong, Shanghai, CN;

Attorney:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61P 35/00 (2006.01); A61K 31/454 (2006.01); A61P 19/00 (2006.01); A61P 25/28 (2006.01); A61P 37/06 (2006.01); A61P 35/02 (2006.01); A61P 25/24 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61P 19/00 (2018.01); A61P 25/24 (2018.01); A61P 25/28 (2018.01); A61P 35/02 (2018.01); A61P 37/06 (2018.01);
Abstract

The present invention relates to an imidazo isoindole derivative, a preparation method therefor and a medical use thereof. In particular, the present invention relates to the imidazo isoindole derivative as shown in the formula (I), a preparation method and pharmaceutical composition containing the derivative, and a use thereof for treating diseases with a pathological characteristic of the IDO-mediated tryptophan metabolic pathways. The diseases comprise cancers, Alzheimer's disease, autoimmune diseases, depression, anxiety disorders, cataracts, psychological disorders and AIDS, wherein the substituents in the formula (I) are the same as those defined in the specification.


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