The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2021

Filed:

Sep. 15, 2017
Applicant:

Vitae Pharmaceuticals, Llc, Madison, NJ (US);

Inventors:

Salvacion Cacatian, Conshohocken, PA (US);

David A. Claremon, Maple Glen, PA (US);

Chengguo Dong, Staten Island, NY (US);

Yi Fan, Doylestown, PA (US);

Lanqi Jia, Horsham, PA (US);

Stephen D. Lotesta, Burlington, NJ (US);

Suresh B. Singh, Kendall Park, NJ (US);

Shankar Venkatraman, Lansdale, PA (US);

Jing Yuan, Lansdale, PA (US);

Yajun Zheng, Hockessin, DE (US);

Linghang Zhuang, Chalfont, PA (US);

Assignee:

VITAE PHARMACEUTICALS, LLC, Madison, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 35/00 (2018.01); C07D 487/04 (2013.01);
Abstract

The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.


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