The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2021

Filed:

Jan. 29, 2019
Applicant:

Incyte Corporation, Wilmington, DE (US);

Inventors:

Dengjin Wang, Wilmington, DE (US);

Pingli Liu, Wilmington, DE (US);

Yongzhong Wu, Glen Mills, PA (US);

Jiacheng Zhou, Newark, DE (US);

Assignee:

Incyte Corporation, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01); C07D 487/04 (2006.01); C07D 213/803 (2006.01); C07D 213/61 (2006.01); C07D 401/04 (2006.01); A61P 27/02 (2006.01); A61P 17/06 (2006.01); A61P 19/02 (2006.01); A61P 19/08 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); C07D 213/61 (2013.01); C07D 213/803 (2013.01); C07D 401/04 (2013.01); C07D 487/04 (2013.01); A61P 17/06 (2018.01); A61P 19/02 (2018.01); A61P 19/08 (2018.01); A61P 27/02 (2018.01); A61P 35/00 (2018.01);
Abstract

This invention relates to processes and intermediates for making {1-{1-[3-fluoro-2-(trifluoromethyl)isonicotinoyl]piperidin-4-yl}-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile, useful in the treatment of diseases related to the activity of Janus kinases (JAK) including inflammatory disorders, autoimmune disorders, cancer, and other diseases.


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