The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2021

Filed:

Jun. 23, 2017
Applicant:

St. Jude Children's Research Hospital, Memphis, TN (US);

Inventors:

Lalit Kumar Sharma, South San Francisco, CA (US);

Richard E. Lee, Cordova, TN (US);

Charles O. Rock, Bartlett, TN (US);

Suzanne Jackowski, Bartlett, TN (US);

Mi Kyung Yun, Collierville, TN (US);

Chitra Subramanian, Cordova, TN (US);

Jiuyu Liu, Collierville, TN (US);

Assignee:
Attorney:
Int. Cl.
CPC ...
C07D 241/04 (2006.01); C07D 237/24 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); A61K 31/501 (2006.01); A61P 3/10 (2006.01); A61P 25/00 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 409/12 (2006.01); C07D 401/12 (2006.01); C07D 213/85 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/501 (2013.01); A61P 3/10 (2018.01); A61P 25/00 (2018.01); C07D 213/85 (2013.01); C07D 237/24 (2013.01); C07D 241/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 409/12 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01);
Abstract

The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


Find Patent Forward Citations

Loading…