The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2021
Filed:
Jun. 29, 2017
Applicant:
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Inventors:
Hideki Moriguchi, Osaka, JP;
Yusuke Tanaka, Osaka, JP;
Tatsunori Ino, Osaka, JP;
Tohru Kambe, Osaka, JP;
Taihei Nishiyama, Osaka, JP;
Shinichiro Tsujiyama, Osaka, JP;
Yohei Ueda, Osaka, JP;
Assignee:
ONO PHARMACEUTICAL CO.. LTD., Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 313/06 (2006.01); C07C 69/65 (2006.01); C07C 69/75 (2006.01); C07D 307/937 (2006.01);
U.S. Cl.
CPC ...
C07D 313/06 (2013.01); C07C 69/65 (2013.01); C07C 69/75 (2013.01); C07D 307/937 (2013.01);
Abstract
A method for producing a compound, such as 2-propanyl 4-{(3S,5aR,6R,7R,8aS)-6-[(1E,3R)-4-(2,5-difluorophenoxy)-3-hydroxy-1-buten-1-yl]-7-hydroxyoctahydro-2H-cyclopenta[b]oxepin-3-yl}butanoate, and a novel intermediate suitable for the method, whereby the compound can be stably supplied with a high total reaction yield, by changing the starting material and improving the metathesis reaction, asymmetric reduction reaction and the like.