The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2021
Filed:
Apr. 29, 2016
Applicant:
Curevac Ag, Tübingen, DE;
Inventors:
Thomas Schlake, Gundelfingen, DE;
Andreas Thess, Kusterdingen, DE;
Assignee:
CureVac AG, Tübingen, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/7105 (2006.01); A61K 38/38 (2006.01); A61K 38/44 (2006.01); C07K 14/76 (2006.01); C12P 19/34 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
A61K 48/005 (2013.01); A61K 31/7105 (2013.01); A61K 38/38 (2013.01); A61K 38/44 (2013.01); C07K 14/76 (2013.01); C12P 19/34 (2013.01); G01N 33/74 (2013.01); C12Y 113/12007 (2013.01);
Abstract
The present invention provides a method for providing modified mRNAs of reduced immunogenicity and/or immunostimulatory capacity for use in protein replacement therapy. The invention further provides modified mRNAs and pharmaceutical compositions comprising the modified mRNAs according to the invention for use in protein replacement therapy.