The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2021

Filed:

Jul. 28, 2017
Applicant:

The Usa, As Represented BY the Secretary, Dept. of Health and Human Services, Bethesda, MD (US);

Inventors:

Barney S. Graham, Rockville, MD (US);

Theodore C. Pierson, Poolesville, MD (US);

Kimberly A. Dowd, Columbia, MD (US);

John R. Mascola, Rockville, MD (US);

Wing-pui Kong, Germantown, MD (US);

Sung-youl Ko, Gaithersburg, MD (US);

Eun Sung Yang, Rockville, MD (US);

Wei Shi, Rockville, MD (US);

Lingshu Wang, North Potomac, MD (US);

Christina R. Demaso, Rockville, MD (US);

Rebecca S. Pelc, Morrisville, NC (US);

Adrian Creanga, Bethesda, MD (US);

Julie Ledgerwood, Bethesda, MD (US);

Leda R. Castilho, Rio de Janeiro, BR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/00 (2006.01); A61K 39/015 (2006.01); C12N 7/00 (2006.01); A61K 39/295 (2006.01); C07K 14/005 (2006.01); G01N 33/536 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C07K 14/005 (2013.01); G01N 33/536 (2013.01); G01N 33/56983 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/53 (2013.01); C07K 2319/02 (2013.01); C07K 2319/33 (2013.01); C12N 2770/24122 (2013.01); C12N 2770/24123 (2013.01); C12N 2770/24134 (2013.01); C12N 2770/24143 (2013.01); C12N 2770/24151 (2013.01); C12N 2770/24171 (2013.01);
Abstract

The present invention relates to a vaccine for Zika virus, the vaccine comprising Zika virus membrane and envelope proteins. More specifically, the vaccine comprises nucleic acid molecules encoding modified Zika virus membrane and/or envelope proteins. When introduced into a cell, the encoded proteins are produced, which results in the production of a virus-like particle capable of eliciting an immune response against Zika virus.


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