The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2021

Filed:

May. 20, 2016
Applicant:

Shanghai Green Valley Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Zhenqing Zhang, Suzhou, CN;

Jie Hao, Suzhou, CN;

Shichang Sun, Suzhou, CN;

Huiling Zhang, Suzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/715 (2006.01); A61P 25/00 (2006.01); A61P 9/10 (2006.01); C07H 1/00 (2006.01); C07H 15/04 (2006.01); C08B 15/04 (2006.01); C08L 1/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/715 (2013.01); A61P 9/10 (2018.01); A61P 25/00 (2018.01); C07H 1/00 (2013.01); C07H 15/04 (2013.01); C08B 15/04 (2013.01); C08L 1/04 (2013.01);
Abstract

An oxidized β-1,4-oligoglucuronic acid, and a preparation method therefor and uses thereof. By using abundant cellulose in the natural world as the raw material, all 6-site hydroxyl groups of the cellulose β-1,4-polyglucose is oxidized into carboxyl groups to form glucuronic acid under the action of a sodium bromide (NaBr)-2,2,6,6-tetramethyl piperidine oxide (TEMPO)-sodium hypochlorite (NaClO) oxidation system, and the oxidized oligoglucuronic acid having an open ring at an end is prepared by controlling reaction conditions. The compound has obvious anti-cerebral ischemia activity, and can be developed into a potential anti-cerebral ischemia drug.


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