The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2021

Filed:

Sep. 12, 2014
Applicants:

Doddabele L. Madhavi, Worcester, MA (US);

Daniel I. Kagan, Belmont, MA (US);

Inventors:

Doddabele L. Madhavi, Worcester, MA (US);

Daniel I. Kagan, Belmont, MA (US);

Assignee:

BIOACTIVES LLC, Worcester, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4745 (2006.01); A61K 31/12 (2006.01); A61K 31/05 (2006.01); A61K 9/107 (2006.01); A61K 9/16 (2006.01); A23L 33/175 (2016.01); A23L 33/105 (2016.01); A23L 33/12 (2016.01); A61K 31/198 (2006.01); A61K 36/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A23L 33/105 (2016.08); A23L 33/12 (2016.08); A23L 33/175 (2016.08); A61K 9/1075 (2013.01); A61K 9/1617 (2013.01); A61K 9/1652 (2013.01); A61K 31/05 (2013.01); A61K 31/12 (2013.01); A61K 31/198 (2013.01); A61K 36/00 (2013.01);
Abstract

The present disclosure describes economical processes to improve the bioavailability of nutraceuticals by formulations that induce micronization and sustained release. The inventive process can be used to increase the solubility and bioavailability of lipophilic and moderately water-soluble nutraceuticals by combining excipients that increase the solubility and induce sustained release of the active compounds. The inventive process also can be used to increase the residence time of highly water-soluble nutraceuticals that are metabolized and eliminated quickly from the body, consequently increasing the therapeutic potential. The disclosed formulations advantageously are freely flowing powders that can be used to formulate with other ingredients into tablets, capsules, or the like; or used as bulk powders.


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