The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2021
Filed:
Nov. 07, 2019
Applicant:
Pharmacyclics Llc, Sunnyvale, CA (US);
Inventors:
Marina Gaillard, Orleans, FR;
Philippe Letellier, Orleans, FR;
Assignee:
Pharmacyclics LLC, Sunnyvale, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/343 (2006.01); C07D 307/85 (2006.01); A61K 31/135 (2006.01); A61K 31/166 (2006.01); A61K 31/185 (2006.01); G01N 23/20 (2018.01); G01V 3/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/343 (2013.01); A61K 31/135 (2013.01); A61K 31/166 (2013.01); A61K 31/185 (2013.01); C07D 307/85 (2013.01); G01N 23/20 (2013.01); G01V 3/14 (2013.01);
Abstract
Described herein are salts of 3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofuran-2-carboxamide, in particular that of formula (I): wherein HA is naphthalene-1,5-disulfonic acid, naphthalene-2-sulfonic acid, oxalic acid, benzenesulfonic acid, or sulfuric acid, or hydrates thereof, and crystalline forms thereof characterized by the powder X-ray diffraction diagram and the 13C CP/MAS NMR solid state spectrum. Also described are compositions, methods of use and preparation thereof.