The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2021

Filed:

Mar. 14, 2019
Applicant:

Qingdao University, Qingdao, CN;

Inventors:

Hui Jin, Qingdao, CN;

Rijun Gui, Qingdao, CN;

Yongxin Fu, Qingdao, CN;

Xiangning Bu, Qingdao, CN;

Assignee:

QINGDAO UNIVERSITY, Qingdao, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); G01N 27/00 (2006.01); C08K 3/22 (2006.01); C09K 11/02 (2006.01); C09K 11/06 (2006.01); C08G 77/26 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); C08G 77/26 (2013.01); C08K 3/22 (2013.01); C09K 11/025 (2013.01); C09K 11/06 (2013.01); C08K 2003/2275 (2013.01); C08K 2201/01 (2013.01); C09K 2211/14 (2013.01); G01N 2021/6439 (2013.01); G01N 2600/00 (2013.01);
Abstract

A method for preparing a ratiometric fluorescent sensor for phycoerythrin based on a magnetic molecularly imprinted core-shell polymer is provided. With FeOmagnetic nanoparticles as the core, blue fluorescence-emitting carbon quantum dots (B-CDs) are coupled on the surfaces of FeOmagnetic nanoparticles, and SiOshells carrying template molecules (phycoerythrin) are grown on the surfaces of FeO/B-CDs. Then, the molecularly imprinted polymer SiO-MIPs are obtained by eluting the template molecules, that is, FeO/B-CDs/SiO-MIPs are obtained. Fluorescence emission spectra of the dispersion of FeO/B-CDs/SiO-MIPs in the presence of different concentrations of phycoerythrin are measured. By fitting the linear relationship between the ratios I/Iof fluorescence emission peak intensities of phycoerythrin and B-CDs and the molar concentrations of phycoerythrin, the ratiometric fluorescent sensor for phycoerythrin is constructed.


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