The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2021
Filed:
Jan. 03, 2019
Applicant:
Bicyclerd Limited, Cambridge, GB;
Inventors:
Assignee:
BicycleRD Limited, Cambridge, GB;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/64 (2006.01); C07K 7/08 (2006.01); C07K 17/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/64 (2013.01); C07K 7/08 (2013.01); C07K 17/00 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are specific for the human and rat protease plasma kallikrein and are modified in one or two peptide loops to enhance potency and/or protease resistance.