The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2021
Filed:
Sep. 15, 2016
Nanomedsyn, Montpellier, FR;
Centre National DE LA Recherche Scientifique - Cnrs, Paris, FR;
Universite DE Montpellier, Montpellier, FR;
Alain Morere, Saint Gely du Fesc, FR;
Afitz Da Silva, Montpellier, FR;
Elise Bouffard, Mignaloux Beauvoir, FR;
Khaled El Cheikh, Montpellier, FR;
Jean-Olivier Durand, Palavas les Plots, FR;
Marie Maynadier, Ceyras, FR;
Ilaria Basile, Saint Gely du Fesc, FR;
NANOMEDSYN, Montpellier, FR;
Centre National de la Recherche Scientifique, Paris, FR;
Universite de Montpellier, Montpellier, FR;
Abstract
The subject matter of the present invention is a compound characterized in that it has the general formula (I): in which P, X, n, A, L and Lare as defined in Claim. The present invention also relates to a process for preparing said compounds (I) and to the use thereof for targeting the cation-independent mannose 6-phosphate receptor (CI-M6PR). The subject matter of the invention is also a conjugate of formula (III): in which P, X, n, A, L and L'are as defined in Claim, and the use thereof: —in a method for therapeutic treatment of the human or animal body, in particular chosen from enzyme replacement therapy, photodynamic therapy or cancer treatment, and/or—in a method of diagnosis, in particular of diseases or of ailments associated with an increase or with a decrease in CI-M6PR expression.