The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2021
Filed:
Dec. 18, 2019
King Abdulaziz University, Jeddah, SA;
Abdelsattar M. Omar, Jeddah, SA;
Mohamed A. El-Zahabi, Cairo, EG;
Salah G. Atteiah, Zagazig, EG;
Ashraf B. Abdel-Naim, Jeddah, SA;
Moustafa E. El-Araby, Jeddah, SA;
King Abdulaziz University, Jeddah, SA;
Abstract
Compounds for the treatment of hyperglycemia and/or diabetes are provided. The compounds, which inhibit the enzyme dipeptidyl peptidase (DPP-4), are based on the structure where n1=0-2 such as 0 or 1; R1 is i) a saturated or unsaturated, substituted or unsubstituted monocyclic aliphatic ring, alone or fused with cyclopropane or cyclobutene, optionally comprising one or more substituents attached to the ring; or ii) a substituted or unsubstituted monocyclic aromatic ring, optionally comprising one or more substituents attached to the ring; R2 is present or absent and if present is: C═O; (CH)where n=0-4; S; SO; SO; NR where R═H, CHor CHCH; or NH(CH)where n=0-4; and R3 is present or absent and if present is (CH)where n=0-4; S; SO; SO; NR where R═H, CHor CHCH; or NH(CH)n where n=0-4; and salts and isomers thereof.