The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2021
Filed:
Apr. 13, 2017
Applicants:
University of Ottawa, Ottawa, CA;
University of Maryland, Baltimore, Baltimore, MD (US);
University of Rochester, Rochester, NY (US);
Inventors:
Jeffrey W. Keillor, Ottawa, CA;
Abdullah Akbar, Ottawa, CA;
Richard L. Eckert, Baltimore, MD (US);
Matthew Fisher, Baltimore, MD (US);
Gail V. W. Johnson, Rochester, NY (US);
Assignees:
UNIVERSITY OF OTTAWA, Ottawa, CA;
UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);
UNIVERSITY OF ROCHESTER, Rochester, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4965 (2006.01); C07D 295/10 (2006.01); C07D 241/04 (2006.01); C07C 317/36 (2006.01); C07D 405/06 (2006.01);
U.S. Cl.
CPC ...
C07D 241/04 (2013.01); C07C 317/36 (2013.01); C07D 405/06 (2013.01);
Abstract
There are provided Tissue Transglutaminase (TG2) inhibitor compounds, and compositions and methods of use thereof for the prevention or treatment of a cancer. Compounds of Formula I, and pharmaceutically acceptable salts thereof, are provided: