The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2021
Filed:
Mar. 13, 2014
Applicant:
Gladiator Biosciences, Inc., Mill Valley, CA (US);
Inventors:
Maxine Bauzon, Hercules, CA (US);
Terry Hermiston, Mill Valley, CA (US);
Assignee:
GLADIATOR BIOSCIENCES, INC., Mill Valley, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61P 31/12 (2006.01); C12N 9/64 (2006.01); A61K 47/64 (2017.01); C07K 14/485 (2006.01); C07K 14/745 (2006.01); C12N 9/74 (2006.01); A61K 38/16 (2006.01); A61K 38/18 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 38/16 (2013.01); A61K 38/1808 (2013.01); A61K 45/06 (2013.01); A61K 47/642 (2017.08); A61N 5/10 (2013.01); A61P 31/12 (2018.01); C07K 14/485 (2013.01); C07K 14/745 (2013.01); C12N 9/6424 (2013.01); C12N 9/6429 (2013.01); C12N 9/6437 (2013.01); C07K 2319/035 (2013.01); C12Y 304/21005 (2013.01); C12Y 304/21021 (2013.01); Y02A 50/30 (2018.01);
Abstract
The disclosure relates to the recombinant Gla domain proteins and their use targeting phosphatidylserine (PtdS) moieties on the surface of cells, particularly those expressing elevated levels of PtdS, such as cells undergoing apoptosis. These proteins can be linked to both diagnostic and therapeutic payloads, thereby permitting identification and treatment of cells expression elevated PtdS.