The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 2021
Filed:
Dec. 27, 2018
Applicant:
Academia Sinica, Taipei, TW;
Inventors:
Assignee:
ACADEMIA SINICA, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/422 (2006.01); A61K 45/06 (2006.01); A61K 31/385 (2006.01);
U.S. Cl.
CPC ...
A61K 31/422 (2013.01); A61K 31/385 (2013.01); A61K 45/06 (2013.01);
Abstract
Disclosed herein are novel uses of a compound of formula (I) as an inhibitor of bacterial two component signal transduction system (TCS),A-L-B-L-A  (I)wherein, A is a moiety having a negative charge; L is —(CH—O)—CH— or a moiety consists of a carbocyclyl and a heterocyclyl respectively having 5 to 10 ring atoms and coupling together, in which n is 0 or 1; and B is a 5 to 10-membered carbocyclyl or heterocyclyl. The compound of formula (I) may suppress or inhibit the growth of bacteria, including the notorious multi-drug resistant bacteria.