The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2021

Filed:

Oct. 17, 2019
Applicant:

Micelle Biopharma, Inc., Riviera Beach, FL (US);

Inventors:

Frederick D. Sancilio, Riviera Beach, FL (US);

Thorsteinn Thorsteinsson, Riviera Beach, FL (US);

Glynis Daniel-Archibald, Riviera Beach, NC (US);

Miguel Lopez-Toledano, Riviera Beach, FL (US);

Ahmed Abd Almalik Ahmed Mohammed Daak, Riviera Beach, FL (US);

Assignee:

Micelle BioPharma, Inc., Riviera Beach, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/232 (2006.01); A61K 9/107 (2006.01); A61K 9/48 (2006.01); A61K 31/05 (2006.01); A61K 31/201 (2006.01); A61K 31/202 (2006.01); A61K 31/353 (2006.01); A61K 31/355 (2006.01); A61K 31/7024 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 31/232 (2013.01); A61K 9/1075 (2013.01); A61K 9/4858 (2013.01); A61K 31/05 (2013.01); A61K 31/201 (2013.01); A61K 31/202 (2013.01); A61K 31/353 (2013.01); A61K 31/355 (2013.01); A61K 31/7024 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01);
Abstract

Described herein are compositions including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided are methods of administering to a subject a composition including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent, wherein the compositions form micelles when in contact with an aqueous medium, and the bioavailability of the omega-3 fatty acid is substantially independent of a food effect. The compositions are useful for treating certain disease states which may include (1) malabsorption syndromes, (2) primary sclerosing cholangitis (PSC), (3) non-alcoholic fatty liver disease (NAFLD), (4) sickle cell disease (SCD), (5) age-related macular degeneration (AMD), and (6) neurodegenerative disease, including, Parkinson's Disease (PD), Alzheimer's Disease (AD), Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease), Epilepsy, Bi-polar Syndrome, traumatic brain injury, peripheral neuropathy, and Multiple Sclerosis (MS). Described are also various dosage forms for administering the compositions and use of the compositions in functional foods. Provided herein are also kits with instructions for their administration.


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