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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10894020 B1

PDFFull Text
Date of Patent:
Jan. 19, 2021

Filed:

Jan. 04, 2019

Hybrid nanoparticles containing boron-doped graphene quantum dots and applications thereof

Applicant:

National Tsing Hua University, Hsinchu, TW;

Inventors:

Shang-Hsiu Hu, Hsinchu, TW;

Yu-Lin Su, Hsinchu, TW;

Assignee:

NATIONAL TSING HUA UNIVERSITY, Hsinchu, TW;

Attorney:

WPAT, PC

Primary Examiner:

Sean M Basquill

Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/00 (2006.01); A61K 31/351 (2006.01); A61K 31/519 (2006.01); A61K 47/69 (2017.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01); B82Y 40/00 (2011.01); B82Y 5/00 (2011.01); B82Y 30/00 (2011.01);
U.S. Cl.
CPC ...
A61K 9/5192 (2013.01); A61K 9/0009 (2013.01); A61K 9/513 (2013.01); A61K 31/351 (2013.01); A61K 31/519 (2013.01); A61K 47/54 (2017.08); A61K 47/6901 (2017.08); A61P 35/00 (2018.01); B82Y 5/00 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01);
Abstract

Provided is a hybrid nanoparticle, including an aggregate assembled from a plurality of polymeric molecules, and a plurality of boron-doped graphene quantum dots localized in the aggregate. The polymeric molecule is preferably a pH-responsive dendrimer; the polymeric molecule and the boron-doped graphene quantum dot may be separately associated with different drugs; and hybrid nanoparticle may further include a targeting molecule, such as a rabies virus glycoprotein. Also provided is a method of controlling disassembly of a hybrid nanoparticle, including applying a high-frequency magnetic field to the hybrid nanoparticle to induce disassembly thereof. Also provided is an application of the hybrid nanoparticle for preparing a tumor-penetrating drug carrier.

Find Patent Forward Citations

Hu, Shang-Hsiu. (2021). Hybrid nanoparticles containing boron-doped graphene quantum dots and applications thereof (U.S. Patent No. 10894020). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10894020

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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