The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2021
Filed:
Sep. 27, 2018
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Sonja Offner, Penzberg, DE;
Friederike Jung, Penzberg, DE;
Assignee:
HOFFMANN-LA ROCHE INC., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0781 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0635 (2013.01); C12N 2501/2301 (2013.01); C12N 2501/231 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2304 (2013.01); C12N 2501/2306 (2013.01); C12N 2501/2321 (2013.01); C12N 2501/25 (2013.01); C12N 2502/1185 (2013.01); C12N 2502/30 (2013.01); C12N 2510/02 (2013.01); C12N 2525/00 (2013.01);
Abstract
Herein is reported a method for co-cultivating one or more B-cells comprising the step of incubating the one or more B-cells with EL4-B5 cells, whereby the EL4-B5 cells have been obtained/are from a cultivation of EL4-B5 cells that has a cell density of from 600,000 cells/ml up to 1,500,000 cells/ml.