The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2021
Filed:
Jan. 07, 2020
Immatics Biotechnologies Gmbh, Tuebingen, DE;
Felix Unverdorben, Stuttgart, DE;
Sebastian Bunk, Tuebingen, DE;
Martin Hofmann, Tuebingen, DE;
Dominik Maurer, Moessingen, DE;
Meike Hutt, Stuttgart, DE;
Claudia Wagner, Tuebingen, DE;
Leonie Alten, Tuebingen, DE;
IMMATICS BIOTECHNOLOGIES GMBH, Tuebingen, DE;
Abstract
The present invention pertains to antigen recognizing constructs against COL6A3 antigens. The invention in particular provides novel engineered T cell receptor (TCR) based molecules which are selective and specific for the tumor expressing antigen COL6A3. The TCR of the invention, and COL6A3 antigen binding fragments derived therefrom, are of use for the diagnosis, treatment and prevention of COL6A3 expressing cancerous diseases. Further provided are nucleic acids encoding the antigen recognizing constructs of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen recognizing constructs and pharmaceutical compositions comprising the compounds of the invention.