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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10889643 B1

PDFFull Text
Date of Patent:
Jan. 12, 2021

Filed:

Jan. 11, 2017

Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof

Applicants:

Novartis Ag, Basel, CH;

Universität Zürich, Zürich, CH;

Inventors:

Natalia Arenas-Ramirez, Zürich, CH;

Iwan Beuvink, Basel, CH;

Onur Boyman, Küsnacht, CH;

Barbara Brannetti, Basel, CH;

Andreas Katopodis, Basel, CH;

Simone Popp, Basel, CH;

Catherine Regnier, Basel, CH;

Chao Zou, Basel, CH;

Assignee:

Universität Zürich, Zürich, CH;

Attorneys:

Michele M. Wales

Inhouse Patent Counsel, LLC

Primary Examiner:

Prema M Mertz

Int. Cl.
CPC ...
C07K 16/24 (2006.01); C12N 5/10 (2006.01); C12N 15/63 (2006.01); C07K 14/55 (2006.01); A61K 39/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/246 (2013.01); C07K 14/55 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/74 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present invention relates to antibodies binding to human interleukin-2 (hIL-2). The invention more specifically relates to humanized antibodies specifically binding a particular epitope of hIL-2 and, when bound to this epitope, displaying a unique capability of inhibiting binding of hIL-2 to CD25.

Find Patent Forward Citations

Arenas-Ramirez, Natalia. (2021). Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof (U.S. Patent No. 10889643). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10889643

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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