The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2021
Filed:
Mar. 18, 2019
William Marsh Rice University, Houston, TX (US);
Bristol-myers Squibb Company, Princeton, NJ (US);
The Scripps Research Institute, La Jolla, CA (US);
Kyriacos C. Nicolaou, Houston, TX (US);
Min Lu, Houston, TX (US);
Debashis Mandal, Houston, TX (US);
Sanjeev Gangwar, Foster City, CA (US);
Naidu S. Chowdari, Dublin, CA (US);
Yam B. Poudel, Fremont, CA (US);
William Marsh Rice University, Houston, TX (US);
The Scripps Research Institute, La Jolla, CA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
In one aspect, the present disclosure provides new analogs of uncialamycin. The present disclosure also provides novel synthetic pathways to obtaining uncialamycin and analogs thereof. Additionally, the present disclosure also describes methods of use of uncialamycin and analogs thereof. In another aspect, the present disclosure provides antibody-drug conjugates which may be used to treat cancer or another disease or disorder.