The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2021

Filed:

Jan. 23, 2018
Applicant:

Ucb Biopharma Srl, Brussels, BE;

Inventors:

Adrian Hall, Brussels, BE;

Laurent Provins, Brussels, BE;

Malcolm Maccoss, Seabrook Island, SC (US);

Assignee:

UCB Biopharma SRL, Brussels, BE;

Attorney:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); A61K 31/496 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/496 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61P 25/28 (2018.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01);
Abstract

The present invention relates to certain bicyclic bis-heteroaryl compounds of Formula (I), pharmaceutical compositions containing them, and methods of using them, including methods for preventing, reversing, slowing, or inhibiting protein aggregation, and methods of treating diseases that are associated with protein aggregation, including neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, Lewy body disease, Parkinson's disease with dementia, fronto-temporal dementia, Huntington's Disease, amyotrophic lateral sclerosis, and multiple system atrophy, and cancer including melanoma.


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