The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2021

Filed:

Dec. 13, 2017
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Jennifer R. Allen, Newbury Park, CA (US);

Albert Amegadzie, Moorpark, CA (US);

Matthew P. Bourbeau, Woodland Hills, CA (US);

Jian J. Chen, Camarillo, CA (US);

Michael J. Frohn, Thousand Oaks, CA (US);

Paul E. Harrington, Thousand Oaks, CA (US);

Jonathan D. Low, Reseda, CA (US);

Vu V. Ma, Oak Park, CA (US);

Thomas T. Nguyen, Newbury Park, CA (US);

Alexander Pickrell, Westlake Village, CA (US);

Corey Reeves, Sherman Oaks, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); C07D 417/14 (2006.01); C07D 417/10 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 417/10 (2013.01);
Abstract

The present disclosure provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I:


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