The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2021

Filed:

Jul. 06, 2017
Applicant:

Cyclerion Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Vasu Sethuraman, Waltham, MA (US);

Ahmad Hashash, Southborough, MA (US);

Song Xue, Newton, MA (US);

Robert C. Livingston, Arlington, MA (US);

Kwame Wiredu Nti-Addae, Tewksbury, MA (US);

Assignee:

Cyclerion Therapeutics, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present disclosure relates to crystalline solid forms of a stimulator of soluble guanylate cyclase (sGC), Compound I: Also provided herein are methods for the preparation of these solid forms. The invention also relates to pharmaceutical formulations and dosage forms comprising these solid forms and their uses thereof, alone or in combination with one or more additional agents, for treating and/or preventing various diseases or disorders; these diseases or disorders are ones that may benefit from sGC stimulation or from an increase in the concentration of nitric oxide (NO) and/or cyclic guanosine monophosphate (cGMP).


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