The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2021
Filed:
Jan. 12, 2018
Academy of Military Medical Sciences, Beijing, CN;
Cheng Zhang, Beijing, CN;
Haoshan Wang, Beijing, CN;
Guoxing Dong, Beijing, CN;
Ning Wu, Beijing, CN;
Shuzhuo Zhang, Beijing, CN;
Xiaomei Zhuang, Beijing, CN;
Chong Pang, Beijing, CN;
Juan Wang, Beijing, CN;
Rifang Yang, Beijing, CN;
Jianquan Zheng, Beijing, CN;
Jin Li, Beijing, CN;
Liuhong Yun, Beijing, CN;
Academy of Military Medical Sciences, Beijing, CN;
Abstract
The invention belongs to the field of medicine and chemical industry and relates to a 4,4-diphenylpiperidine compound or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same and uses thereof. In particular, the invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, and to a pharmaceutical composition comprising the compound or a pharmaceutically acceptable salt thereof. In the present invention, the compound or pharmaceutically acceptable salt thereof and the pharmaceutical composition have significant activity in blocking an N-type calcium channel, and have good pharmacokinetic properties, can effectively relieve pain, and have a potential as a new medicament for prevention or treatment of pain, stroke, cerebral ischemia, alcohol addiction, alcoholism, kidney disease, addictive disorder caused by analgesic or tolerance disorder caused by analgesic.