The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2021
Filed:
Aug. 30, 2019
Daewoong Pharmaceutical Co., Ltd., Gyeonggi-do, KR;
Green Cross Corporation, Gyeonggi-do, KR;
Hee-kyoon Yoon, Cheongju-si, KR;
Se-Hwan Park, Yongin-si, KR;
Ji-sung Yoon, Yongi-si, KR;
Soongyu Choi, Yongin-si, KR;
Hee Jeong Seo, Yongin-si, KR;
Eun-Jung Park, Yongin-si, KR;
Younggyu Kong, Yongin-si, KR;
Kwang-Seop Song, Yongin-si, KR;
Min Ju Kim, Yongin-si, KR;
So Ok Park, Yongin-si, KR;
DAEWOONG PHARMACEUTICAL CO., LTD., Hwaseong-si, KR;
GREEN CROSS CORPORATION, Yongin, KR;
Abstract
The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing.