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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10889560 B1

PDFFull Text
Date of Patent:
Jan. 12, 2021

Filed:

Dec. 15, 2017

4-amino-2-pyrido-bicyclic pyrimidines and use thereof as topoisomerase ii inhibitors

Applicants:

Fondazione Istituto Italiano Di Tecnologia, Genoa, IT;

Alma Mater Studiorum—universita' Di Bologna, Bologna, IT;

Universita' Degli Studi Di Padova, Padua, IT;

Inventors:

Marco De Vivo, Genoa, IT;

Jose Antonio Ortega Martinez, Genoa, IT;

Jose Manuel Arencibia Jimenez, Genoa, IT;

Anna Minarini, Bologna, IT;

Claudia Sissi, Cadoneghe, IT;

Assignees:

UNIVERSITÀ DEGLI STUDI DI PADOVA, Padua, IT;

ALMA MATER STUDIORUM-UNIVERSITÀ DI BOLOGNA, Bologna, IT;

FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA, Genoa, IT;

Attorney:

Troutman Pepper Hamilton Sanders LLP (Rochester)

Primary Examiner:

Brian E McDowell

Int. Cl.
CPC ...
C07D 401/04 (2006.01); A61K 33/243 (2019.01); A61K 31/167 (2006.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/357 (2006.01); A61K 31/407 (2006.01); A61K 31/4745 (2006.01); A61K 31/475 (2006.01); A61K 31/513 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/655 (2006.01); A61K 31/704 (2006.01); A61K 31/706 (2006.01); A61K 31/7076 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/167 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/357 (2013.01); A61K 31/407 (2013.01); A61K 31/475 (2013.01); A61K 31/4745 (2013.01); A61K 31/513 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/655 (2013.01); A61K 31/704 (2013.01); A61K 31/706 (2013.01); A61K 31/7076 (2013.01); A61K 33/243 (2019.01); C07D 471/04 (2013.01);
Abstract

The present invention concerns 4-amino-2-pyrido-bicyclic pyrimidines of Formula (I) that function as type II topoisomerase inhibitors and their use thereof as medicaments especially in the treatment of cancer. The invention also provides a method for the manufacture of 4-amino-2-pyrido bicyclic pyrimidines of Formula (I).

Find Patent Forward Citations

De Vivo, Marco. (2021). 4-amino-2-pyrido-bicyclic pyrimidines and use thereof as topoisomerase ii inhibitors (U.S. Patent No. 10889560). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10889560

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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