The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2021

Filed:

Dec. 19, 2014
Applicant:

The Governing Council of the University of Toronto, Toronto, CA;

Inventors:

Patrick Thomas Gunning, Mississauga, CA;

Dziyana Kraskouskaya, Mississauga, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6816 (2018.01); G01N 33/68 (2006.01); G01N 33/52 (2006.01); C07D 257/02 (2006.01); C07C 233/44 (2006.01); C07C 233/80 (2006.01); C07D 403/10 (2006.01); C07D 401/12 (2006.01); C09B 57/00 (2006.01); C09B 1/00 (2006.01); C07C 309/65 (2006.01); C07D 213/38 (2006.01);
U.S. Cl.
CPC ...
C07D 257/02 (2013.01); C07C 233/44 (2013.01); C07C 233/80 (2013.01); C07C 309/65 (2013.01); C07D 213/38 (2013.01); C07D 401/12 (2013.01); C07D 403/10 (2013.01); C09B 1/00 (2013.01); C09B 57/00 (2013.01); C09B 57/001 (2013.01); C12Q 1/6816 (2013.01); G01N 33/52 (2013.01); G01N 33/6842 (2013.01); G01N 2440/14 (2013.01);
Abstract

The present application is directed to excimer forming compounds of Formula I: W—V—[Y]wherein W is an excimer forming fluorophore, V is a linker moiety, Y is a metal ion coordinating moiety and n is 1, 2 or 3. In particular, the application is directed to excimer forming compounds for the detection of proximally phosphorylated sites including those found on polypeptides, proteins, pyrophosphate and RNA, for example in aqueous solution, polyacrylamide gels blotting membranes, solid-support assays and in cell culture samples.


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