The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2021
Filed:
Sep. 13, 2019
Applicant:
The Governing Council of the University of Toronto, Toronto, CA;
Inventors:
Shana Olwyn Kelley, Toronto, CA;
Edward Hartley Sargent, Toronto, CA;
Justin David Besant, Toronto, CA;
Assignee:
The Governing Council of the University of Toronto, Toronto, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 33/49 (2006.01); G01N 35/00 (2006.01); G01N 33/48 (2006.01); G01N 1/40 (2006.01); C12Q 1/02 (2006.01); G01N 33/50 (2006.01); G01N 33/487 (2006.01); G01N 33/493 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); C12Q 1/02 (2013.01); G01N 1/40 (2013.01); G01N 33/48735 (2013.01); G01N 33/49 (2013.01); G01N 33/493 (2013.01); G01N 33/5005 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/0673 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0633 (2013.01);
Abstract
Methods and devices for detecting metabolic activity of target cells in a sample. The target cells are concentrated in a nanoliter well having a microfilter. A reporter compound that exhibits a change in electrochemical state in response to metabolic activity of the target cells is introduced. Metabolic activity or viability of the target cells is detected based on a determined change in the electrochemical state of contents in the well.