The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2021

Filed:

Feb. 10, 2017
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Karl Dane Wittrup, Boston, MA (US);

Darrell J. Irvine, Arlington, MA (US);

Cary Francis Opel, Somerville, MA (US);

Kelly Dare Moynihan, Allston, MA (US);

Jennifer R. Cochran, Stanford, CA (US);

Byron Hua Kwan, Seattle, WA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 38/16 (2006.01); C07K 16/28 (2006.01); A61K 39/12 (2006.01); A61K 47/64 (2017.01); A61K 47/60 (2017.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C07K 16/30 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2013 (2013.01); A61K 38/16 (2013.01); A61K 39/0011 (2013.01); A61K 39/12 (2013.01); A61K 39/3955 (2013.01); A61K 39/39541 (2013.01); A61K 39/39558 (2013.01); A61K 47/60 (2017.08); A61K 47/643 (2017.08); A61K 47/6813 (2017.08); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); C07K 16/3053 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/55533 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/585 (2013.01); A61K 2039/6018 (2013.01); A61K 2039/6025 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6056 (2013.01); A61K 2039/6093 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01); C12N 2710/20034 (2013.01);
Abstract

The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), an integrin-binding-Fc fusion protein, and a cancer vaccine. The methods of the invention can be used to treat a broad range of cancer types.


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