The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2021
Filed:
Jul. 31, 2017
Applicants:
Astellas Pharma Inc., Chuo-ku, Tokyo, JP;
National University Corporation Tottori University, Tottori-shi, Tottori, JP;
Inventors:
Assignees:
National University Corporation Tottori University, Tottori, JP;
Astellas Pharma Inc., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/863 (2006.01); A61K 48/00 (2006.01); A61K 35/76 (2015.01); C12N 7/01 (2006.01); C07K 14/54 (2006.01); A61K 35/768 (2015.01); C12N 7/00 (2006.01); A61K 38/20 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 38/208 (2013.01); A61K 38/2046 (2013.01); A61K 48/005 (2013.01); C07K 14/5418 (2013.01); C07K 14/5434 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 2710/24132 (2013.01); C12N 2710/24143 (2013.01); C12N 2710/24162 (2013.01); C12N 2710/24171 (2013.01);
Abstract
The present invention provides a genetically recombinant vaccinia virus effective in preventing or treating cancer. Specifically, the present invention provides a vaccinia virus comprising two polynucleotides, a polynucleotide encoding IL-7 and a polynucleotide encoding IL-12; a combination kit of two vaccinia viruses, a vaccinia virus comprising a polynucleotide encoding IL-7 and a vaccinia virus comprising a polynucleotide encoding IL-12; and use of the two vaccinia viruses in combination.