The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2021

Filed:

Jun. 24, 2019
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Philip Jones, Houston, TX (US);

Maria Emilia Di Francesco, Houston, TX (US);

Timothy McAfoos, Pearland, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); C07D 413/14 (2006.01); A61K 31/4245 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01); A61K 31/4709 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01);
U.S. Cl.
CPC ...
A61K 31/454 (2013.01); A61K 31/4245 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); C07D 413/14 (2013.01);
Abstract

The present disclosure relates to salts of heterocyclic compounds and methods that inhibit HIF pathway activity. The compounds are designed to treat or prevent cancer and other hypoxia-mediated diseases.


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