The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2021

Filed:

Mar. 07, 2017
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Mohammad O. Hoque, Baltimore, MD (US);

David Sidransky, Baltimore, MD (US);

Akira Oki, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/33 (2006.01); A61K 31/415 (2006.01); A61K 31/40 (2006.01); A61K 31/409 (2006.01); A61K 31/407 (2006.01); A61P 35/00 (2006.01); A61K 31/635 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/415 (2013.01); A61K 31/407 (2013.01); A61K 31/409 (2013.01); A61K 31/635 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract

Methods for preventing or treating subjects having cancer based on the identification of pharmaceutical agents that target cancer stem cells (CSCs) have been identified. These methods include administering to the subject an effective amount of a COX2 inhibitor and an effective amount of a YAP1 inhibitor. In addition, methods of enhancing chemotherapeutic responses in cancer patients have been discovered and are described herein.


Find Patent Forward Citations

Hoque, Mohammad. (2021). Pharmaceutical agents targeting cancer stem cells (U.S. Patent No. 10888549). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10888549

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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