The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2021

Filed:

Aug. 23, 2019
Applicant:

Dsm Ip Assets, B.v., Heerlen, NL;

Inventors:
Assignee:

DSM IP ASSETS B.V., Heerlen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61K 47/34 (2017.01); A61K 31/5575 (2006.01); A61F 9/00 (2006.01); A61F 9/007 (2006.01); A61K 9/00 (2006.01); C08G 69/36 (2006.01); C08G 69/44 (2006.01); C08L 77/12 (2006.01); A61F 9/008 (2006.01);
U.S. Cl.
CPC ...
A61K 9/70 (2013.01); A61F 9/0008 (2013.01); A61F 9/0017 (2013.01); A61F 9/00781 (2013.01); A61K 9/0051 (2013.01); A61K 31/5575 (2013.01); A61K 47/34 (2013.01); C08G 69/36 (2013.01); C08G 69/44 (2013.01); C08L 77/12 (2013.01); A61F 2009/00872 (2013.01); A61F 2009/00891 (2013.01);
Abstract

The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which polymer backbone comprises pendant ester and acid functionalities and in which the shell comprises a hydrolytic degradable polymer Y. The hydrolytic degradable polymers X and Y are different polymers. Polymer X further comprises amino-acids in the polymer backbone and degrades via zero order degradation kinetics for a period of at least 3 months. Polymer Y degrades via auto-acceleration degradation kinetics.


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