The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2021

Filed:

Jul. 25, 2017
Applicant:

Inke, S.a., Castellbisbal-Barcelona, ES;

Inventors:

Josep Terradas Camins, Castellbisbal-Barcelona, ES;

Josep Maria Carulla Oliver, Castellbisbal-Barcelona, ES;

Silvia Donnici Garcia, Castellbisbal-Barcelona, ES;

David Gomez Lamarca, Castellbisbal-Barcelona, ES;

Maria Jose Martinez Velon, Sant Joan Despi-Barcelona, ES;

Emma Recio Soler, Sant Joan Despi, ES;

Assignee:

INKE, S.A., Castellbisbal, ES;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61J 3/02 (2006.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 31/40 (2006.01); A61K 31/4015 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61J 3/02 (2013.01); A61K 9/0075 (2013.01); A61K 9/14 (2013.01); A61K 31/40 (2013.01); A61K 31/4015 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention provides a new process for stabilizing the particle size of micronized glycopyrronium salt (such as glycopyrronium bromide) which yields a micronized product exhibiting improved chemical and polymorphic stability even after prolonged storage. The invention also relates to compositions comprising said stabilized glycopyrronium salt (such as glycopyrronium bromide) and to dry powder inhaler devices and capsules or blisters comprising the stabilized glycopyrronium salt (such as glycopyrronium bromide). The glycopyrronium salt (such as glycopyrronium bromide) or compositions of the invention may be used as a medicament, for instance in the treatment of asthma, chronic obstructive pulmonary disease or cystic fibrosis or related diseases.


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