The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2021

Filed:

Dec. 13, 2017
Applicant:

Commissariat a L'energie Atomique ET Aux Energies Alternatives, Paris, FR;

Inventors:

Adrien Mombrun, Grenoble, FR;

Mohamed-Ali Bouamrani, Grenoble, FR;

Celine Le Clec'h, Teche, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/04 (2006.01); G01N 1/28 (2006.01); G01N 33/68 (2006.01); G01N 1/40 (2006.01);
U.S. Cl.
CPC ...
H01J 49/0418 (2013.01); G01N 1/28 (2013.01); G01N 1/405 (2013.01); G01N 33/6851 (2013.01); G01N 2560/00 (2013.01);
Abstract

The invention is a method for capturing biological species present in a body tissue. The method comprises an arrangement of tissue on a support, referred to as a capture support, capable of selectively capturing one or more biological species, referred to as species of interest. The method comprises; —a step of depositing a lysis reagent on the tissue; —a step of droplet formation, on the surface of the tissue, each droplet comprising the solubilized lysis reagent; —a formation of lysis sites, in the tissue, between each droplet and the capture support, such that at each lysis site, species of interest are freed and captured by the capture support.


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