The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2021
Filed:
Nov. 26, 2015
Applicant:
Danziger Innovations Ltd., Moshav Mishmar HaShiva, IL;
Inventors:
Alexander Vainstein, Rechovot, IL;
Ira Marton, Rechovot, IL;
Arik Honig, Rehovot, IL;
Elena Marhevka, Rechovot, IL;
Assignee:
Danziger Innovations Ltd., Moshav Mishmar HaShiva, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8213 (2013.01); C12N 15/8203 (2013.01); C12N 15/8216 (2013.01); C12N 15/8271 (2013.01); C12N 15/8274 (2013.01); C12N 15/8279 (2013.01); C12N 2310/20 (2017.05);
Abstract
A nucleic acid construct is provided. The construct comprises a tobacco rattle virus (TRV) sequence and a nucleic acid sequence encoding a single guide RNA (sgRNA) that mediates sequence-specific cleavage in a target sequence of a genome of interest, wherein the TRV sequence is devoid of a functional 2b sequence. Also provided are plant cells comprising the construct and uses of the construct in gene editing.