The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10883085 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 05, 2021

Filed:

Jan. 29, 2015
Applicant:

Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Shandong, CN;

Inventors:

Jiaqiang Wu, Shandong, CN;

Jiang Yu, Shandong, CN;

Yuyu Zhang, Shandong, CN;

Xiwang Zhu, Shandong, CN;

Yijun Du, Shandong, CN;

Jun Li, Shandong, CN;

Xiaoyan Cong, Shandong, CN;

Jinbao Wang, Shandong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/00 (2006.01); C12N 7/00 (2006.01); C07K 14/005 (2006.01); A61K 38/00 (2006.01); A61P 31/14 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 39/12 (2013.01); A61P 31/14 (2018.01); A61K 2039/5254 (2013.01); A61K 2039/543 (2013.01); A61K 2039/545 (2013.01); A61K 2039/552 (2013.01); C12N 2770/10021 (2013.01); C12N 2770/10034 (2013.01); C12N 2770/10064 (2013.01);
Abstract

The present invention relates to porcine reproductive and respiratory syndrome virus (PRRSV) vaccines in a field of veterinary biological products, and more particularly to a PRRSV SX-105 strain having a deposit number of CGMCC No. 9906, and a use thereof in preparing PRRSV live vaccines. PRRSV SX-1 original strains are strongly pathogenic to swine. A PRRSV SX-105 attenuated strain shows safety and good immunogenicity on the swine. The PRRSV live vaccines, prepared from the PRRSV SX-105 strain, are safe and reliable, and able to generate strong immunity after immunization. The PRRSV live vaccines significantly decrease morbidity and mortality in inoculated swine groups, and have immunization effects reaching and slightly better than conventional commercial vaccines on the market, showing advantages to compete with the same kind of products around the world. The PRRSV live vaccines are capable of effectively preventing PRRS epidemic and transmission, and has broad application prospects.


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