The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2021
Filed:
Jan. 07, 2016
Gilead Sciences, Inc., Foster City, CA (US);
Ling-Jie Gao, Heverlee, BE;
Piet André Maurits Maria Herdewijn, Rotselaar/Wezemaal, BE;
Steven Cesar Alfons De Jonghe, Brussels, BE;
William John Watkins, Saratoga, CA (US);
Lee Shun Chong, Newark, CA (US);
Gilead Sciences, Inc., Foster City, CA (US);
Abstract
This invention provides quinazoline derivatives represented by the structural formula: (I); wherein: Ris hydrogen, NR'R″, Calkyl, arylCalkyl or Ccycloalkyl; Ris amino, Calkyl, Calkenyl, Ccycloalkyl, Ccycloalkenyl, aryl, heterocyclic, arylalkyl, heterocyclic-substituted Calkyl or Ccycloalkyl-Calkyl; Ris hydrogen or Calkyl, or Rand Rtogether with the nitrogen atom to which they are attached form a heterocyclic ring; Y is a single bond, Calkylene, Calkenylene or Calkynylene; Ris halogen, heteroaryl or aryl; R′ and R″ are each independently hydrogen, Calkyl-carbonyl or Calkyl; provided that Ris not phenyl substituted with morpholino when Ris H and Ris H, and provided that when NRRis piperazinyl, said NRRis either non-substituted or substituted with methyl or acetyl; a pharmaceutically acceptable addition salt, a stereoisomer, a mono- or a di-N-oxide, a solvate or a pro-drug thereof, for the treatment of viral infections.