The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2021

Filed:

Mar. 17, 2016
Applicant:

The University of Kansas, Lawrence, KS (US);

Inventors:

Cory Berkland, Lawrence, KS (US);

Joshua Sestak, Lawrence, KS (US);

Teruna J. Siahaan, Lawrence, KS (US);

Assignee:

The University of Kansas, Lawrence, KS (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01); A61K 39/385 (2006.01); A61K 47/54 (2017.01); A61K 47/61 (2017.01); A61K 47/59 (2017.01); A61K 47/69 (2017.01); C07B 43/00 (2006.01); A61K 31/436 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0008 (2013.01); A61K 31/436 (2013.01); A61K 39/385 (2013.01); A61K 47/549 (2017.08); A61K 47/593 (2017.08); A61K 47/61 (2017.08); A61K 47/6933 (2017.08); A61K 47/6937 (2017.08); C07B 43/00 (2013.01); A61K 47/6939 (2017.08); A61K 2039/6093 (2013.01); A61K 2039/627 (2013.01);
Abstract

Bifunctional conjugate compositions are provided comprising a Signal-1 moiety bound to a first polymer carrier, wherein the combined size of the Signal-1 moiety and the first polymer carrier is about 1 nanometer to about 500 nanometers; and a Signal-2 moiety bound to a second polymer carrier, wherein the combined size of the Signal-2 moiety and the second polymer carrier is about 1 nanometer to about 500 nanometers. In some embodiments, the Signal-1 moiety and the Signal-2 moiety are bound to the same polymer carrier. Associated methods are also provided.


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